Comparison of Biolimus-eluting Biodegradable Polymer, Everolimus-eluting and Sirolimus-eluting Coronary Stents

Comparison of Biolimus-eluting Biodegradable Polymer, Everolimus-eluting and Sirolimus-eluting Coronary Stents

To compare the safety and efficacy of coronary stenting with everolimus-eluting stent (Promus Element®) and biolimus-eluting stent with biodegradable polymer (Nobori®)

Inclusion Criteria:

• Significant coronary artery stenosis (> 50% by visual estimate)
• Stable angina, unstable angina, Non-ST elevation myocardial infarction (NSTEMI) and documented silent ischemia
• Patients eligible for intracoronary stenting
• age ≥ 20 years old

Exclusion Criteria:

• ST segment elevation myocardial infarction (within 24 hours)
• Low ejection fraction (< 25%)
• Cardiogenic shock
• History of bleeding diathesis or known coagulopathy
• Limited life-expectancy (less than 1 year) due to combined serious disease
• Contraindication to heparin, sirolimus, everolimus and biolimus
• Contraindication to aspirin and clopidogrel
• Pregnancy