Study of Individualized Physiotherapy for Airway Clearance in Cystic Fibrosis.

Efficacy Study of Physiotherapy for Airway Clearance in Cystic Fibrosis. Randomized Controlled Trials in Single Subjects (N of 1 RCT's).

The purpose of this study is to investigate individual efficacy in Physiotherapy for Airway Clearance, and to investigate user experience, i.e.utility value and preference.

Inclusion Criteria:

• Diagnosis: CF
• Age >18 years
• Amount of sputum >5 ml/60 min
• Wet inhalation of saline/DNase/both
• Informed consent

Exclusion Criteria:

• Respiratory failure
• Hemoptysis
• Bacteriology (burkholderia cephacia, multi-resistent pseudomonas aeruginosa, atypical mycobacteria, MRSA).
• Ongoing intravenous medication
• Pregnancy