Results of Adjunctive Intraoperative Bevacizumab Injection on Trabeculectomy Outcome

The Results of Adjunctive Intraoperative Bevacizumab Injection on Trabeculectomy Outcome: A Randomized Controlled Trial

The purpose of this study is to evaluate the adjunctive effect of intratenon Bevacizumab on the result of trabeculectomy in primary term of intraocular pressure (IOP).

Prospective interventional clinical trial

Single center, outcome assessor-masked, active control, randomized controlled trial

Inclusion Criteria:

• Primary open angle glaucoma with primary mmc-trabeculectomy indication

Exclusion Criteria:

• combined phacoemulsification with trabeculectomy
• no more than 6 month of cataract surgery before trabeculectomy
• revised trabeculectomy
• active uveitic glaucoma
• neovascular glaucoma
• par planar vitrectomy
• conjunctival surgery
• allergy to bevacizumab or mitomycin C
• ischemic heart disease
• cerebrovascular disease
• renal failure
• liver failure