Safety and Pharmacokinetics of Azelaic Acid Foam, 15% in Papulopustular Rosacea

Investigator-blinded, Randomized, Cross-over, Multiple Dose Phase I Study on Safety and Pharmacokinetics of Topically Applied Azelaic Acid Foam, 15% Compared to Azelaic Acid Gel, 15% in Subjects With Papulopustular Rosacea

Assessment of pharmacokinetics of Azelaic Acid Foam after repeated skin application and in comparison to Azelaic Acid gel.

Assessment of safety after repeated skin application.

Inclusion Criteria:

• diagnosis of moderate papulopustular rosacea
• free of any clinically significant disease

Exclusion Criteria:

• body weight less than 50 or more than 130 kg
• clinically significant disease which could interfere with the study