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Dietary fibers likely have a role in body weight management. They may increase satiety and, as a consequence, reduce energy intake during the next meal. There are, however, many different types of dietary fiber, which have diverse physical properties and can therefore impact these outcomes differently. It is, however, unclear whether dietary fibers with different properties lead to differences in energy intake during the next meal. The objective of this study is to study the effect of pectin in 4 different physicochemical states on ad libitum energy intake and possible underlying mechanisms; i.e. gastrointestinal hormones, gastric emptying rate, feelings of satiety and the method of fiber supplementation. We hypothesize that viscous and gelling fibers will reduce ad libitum energy intake compared to low viscous and low gelling fibers.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| control | Placebo Comparator | No additions of fiber to a breakfast meal |
|
| low viscous, low gelling | Active Comparator | low viscous, low gelling fibre added to breakfast meal |
|
| high viscous, low gelling | Active Comparator | high viscous, low gelling fibre added to breakfast meal |
|
| low viscous, high gelling | Active Comparator | low viscous, high gelling fibre added to breakfast meal |
|
| high viscous, high gelling | Active Comparator | high viscous, high gelling fibre added to breakfast meal |
|
| fibre supplement | Active Comparator |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| control: no fiber addition | Dietary Supplement | liquid breakfast without addition of fiber |
| |
| Measure | Description | Time Frame |
|---|---|---|
| energy intake | 3 hours after ingesting the test breakfast ad libitum energy intake is measured. | 3 hours |
| Measure | Description | Time Frame |
|---|---|---|
| appetite sensations | appetite is measured by VAS scales over a period of 3 hours after ingestion of a test breakfast | 3 hours |
| satiety hormones | satiety hormones (ghrelin, PYY, GLP-1, CCK) are measured over a period of 3 hours after ingestion of a test breakfast |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Edith Feskens, PHd | Wageningen University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Wageningen University | Wageningen | 6702 | Netherlands |
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| ID | Term |
|---|---|
| D062408 | Breakfast |
| ID | Term |
|---|---|
| D062407 | Meals |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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high viscous, high gelling fibre is added, not to the breakfast meal, but as supplement |
|
| breakfast with low viscous, low gelling pectin |
| Dietary Supplement |
10g of low viscous, low gelling pectin dissolved in a liquid breakfast |
|
| high viscous, low gelling pectin | Dietary Supplement | 10g of high viscous, low gelling pectin dissolved in a liquid breakfast |
|
| low viscous, high gelling pectin | Dietary Supplement | 10g of low viscous, high gelling pectin dissolved in a liquid breakfast |
|
| high viscous, high gelling pectin | Dietary Supplement | 10g of high viscous, high gelling pectin dissolved in a liquid breakfast |
|
| pectin supplement | Dietary Supplement | 10g of high viscous, high gelling pectin provided as a dietary supplement, a liquid breakfast is served seperately |
|
| 3 hours |
| gastric emptying rate | gastric emptying rate is measured over a period of 3 hours after ingestion of a test breakfast | 3 hours |
| method of supplementation | One of the fibers will be offered as tablets that will be ingested with a glass of water right after the test meal. | 3 hours |
| D019602 |
| Food and Beverages |