Pharmacokinetics Of Alprazolam Sublingual Tablet Versus Conventional Tablet

Open-label, Randomized, Single-Dose, 2 Way Crossover Bioequivalence Study Comparing A New Alprazolam Sublingual Tablet Formulation To A Reference Alprazolam Immediate Release Tablet

To assess if the sublingual tablet will have similar pharmacokinetics as the conventional tablet of alprazolam.

Inclusion Criteria:

• Healthy male and/or female subjects between the ages of 18 and 55 years, inclusive.
• Body Mass Index (BMI) of 17.5 to 30.5 kg/m2.
• Signed informed consent.

Exclusion Criteria:

• Evidence or history of clinically significant abnormalities
• Positive drug screen, excessive alcohol and tobacco use