This is a report of 10 years results of combined Transpupillary thermotherapy (TTT) treatment with Indocyanine green (ICG) in controlling small and medium-sized choroidal melanomas.

The study was done in a Clinical practice setting. Forty six eyes of 46 patients with small or medium-sized choroidal melanomas were treated with i-TTT using infrared light delivered from a diode laser. All patients were evaluated to rule out systemic metastasis and underwent a complete ophthalmological evaluation including: Slit lamp biomicroscopy, dilated fundus examination, Fluorescein angiography, Optical coherence tomography and A/B ultrasonography. Main outcome measures were: Changes in visual acuity, complications associated with the treatment and local control of the tumor.

Inclusion Criteria:

• Small and medium-sized choroidal melanoma
• Patients older than 18 years old.
• Patients who can read and signed the informed consent.

Exclusion Criteria:

• Patients with ocular inflammation.
• Patients with another active ocular disease.

Subjects selected from retina specialist general patient population.