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| ID | Type | Description | Link |
|---|---|---|---|
| Other | Other Grant/Funding Number | [NMRC/TCR/002 - SERI/2008 - TCR 621/41/2008] |
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Emtosecond lasers are used in cutting the flap in LASIK procedures (laser corrective surgery for refractive error). Their use has decreased the incidence of serious complications when compared to the use of microkeratomes(mechanical blades). The commonest femtosecond laser currently used is 'Intralase'. A newer femtosecond laser 'Visumax' (Zeiss) is now available and differs from the Intralase in that it does not interfere with the curvature of the cornea when creating the flap. The Intralase applanates the cornea flat during flap creation which causes the intraocular pressure to be higher. Both Intralase and Visumax lasers are available to patients and surgeons to use at SNEC. The aim of the investigators study is to compare the two lasers in a randomization of left and right eyes in the same patient. The investigators want to measure any difference that the lower intraocular pressure may have during the creation of the flap. This will be measured with a questionaire on patient experience during the procedure and the outcomes of vision, refraction, contrast sensitivity, wave-front analysis, tear function,corneal sensation and flap thickness measured with anterior segment OCT during the post-operative follow up period. To date no-one has compared the use of these two femtosecond lasers. Both lasers are currently used clinically for flap creation at SNEC.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 IntraLase flaps | Patients who have undergone flap creation with IntraLase laser | ||
| 2 Visumax flaps | Patients who have undergone flaps created with Visumax laser |
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| Measure | Description | Time Frame |
|---|---|---|
| Visual Acuity | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| complications | 3 months | |
| Subjective questionnaire | 1 weekd | |
| Corneal Sensation |
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Inclusion Criteria:
Exclusion Criteria:
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Myopic patients presenting to refractive service eligible for LASIK
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| Name | Affiliation | Role |
|---|---|---|
| Donald Tan | Singapore National Eye Centre | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Singapore National Eye Centre | Singapore | 168751 | Singapore |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24801511 | Derived | D'Souza S, Petznick A, Tong L, Hall RC, Rosman M, Chan C, Koh SK, Beuerman RW, Zhou L, Mehta JS. Comparative analysis of two femtosecond LASIK platforms using iTRAQ quantitative proteomics. Invest Ophthalmol Vis Sci. 2014 May 6;55(6):3396-402. doi: 10.1167/iovs.14-14113. |
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| ID | Term |
|---|---|
| D009216 | Myopia |
| ID | Term |
|---|---|
| D012030 | Refractive Errors |
| D005128 | Eye Diseases |
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| 3 months |
| Tear function | 3 months |
| Wavefront analysis | 3 months |
| Contrast Sensitivity | 3 months |