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To compare the renal protective properties of two currently used anaesthetic techniques - a sevoflurane-remifentanil/sufentanil combination with a propofol-remifentanil/sufentanil combination for anaesthesia in patients undergoing living donor kidney donation/transplantation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SEVO | Active Comparator | sevoflurane-remifentanil/sufentanil combination |
|
| SERE | Active Comparator | volatile agent only during reperfusion |
|
| propofol | Active Comparator | propofol-remifentanil/sufentanil |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| procedure:sevoflurane-remifentanil/sufentanil | Drug | Active Comparator |
| |
| Measure | Description | Time Frame |
|---|---|---|
| To compare the renal protective properties of two currently used anaesthetic techniques | participants will be followed for the duration of hospital stay |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| M.M.R.F Struys, Prof.dr. | University Medical Center Groningen | Principal Investigator |
| R,J. Ploeg, Prof.dr | University Medical Center Groningen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Medical Center Groningen | Groningen | 9713 EZ | Netherlands |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28510740 | Derived | Nieuwenhuijs-Moeke GJ, Nieuwenhuijs VB, Seelen MAJ, Berger SP, van den Heuvel MC, Burgerhof JGM, Ottens PJ, Ploeg RJ, Leuvenink HGD, Struys MMRF. Propofol-based anaesthesia versus sevoflurane-based anaesthesia for living donor kidney transplantation: results of the VAPOR-1 randomized controlled trial. Br J Anaesth. 2017 May 1;118(5):720-732. doi: 10.1093/bja/aex057. |
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| ID | Term |
|---|---|
| D017409 | Sufentanil |
| ID | Term |
|---|---|
| D005283 | Fentanyl |
| D010880 | Piperidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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| volatile agent only during reperfusion |
| Drug |
Active Comparator |
|
| propofol-remifentanil/sufentanil | Drug | Active Comparator |
|