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| Name | Class |
|---|---|
| Technion, Israel Institute of Technology | OTHER |
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Parkinson's disease is diagnosed clinically, because biomarkers that may help in diagnosis and differential diagnosis are not yet available. Exhaled breath testing may yield a "breath-print" that can be used to distinguish healthy and diseased states.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with parkinsonism | Patients suffering from Parkinson's disease or parkinsonism |
| |
| Healthy controls | Patients not suffering from Parkinson's disease or any other neurological disorder |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| collection of exhaled breath | Other | no intervention |
|
| Measure | Description | Time Frame |
|---|---|---|
| Nanosensory detection | analyze combinations of nanomaterial-based sensors (organically functionalized carbon nanotubes and gold nanoparticles) | immediate |
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Inclusion Criteria:
Exclusion Criteria:
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Patients diagnosed with Idiopathic Parkinson's disease and Parkinsonism will be included.
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| Name | Affiliation | Role |
|---|---|---|
| Ilana Schlesinger, MD | Rambam Health Care Campus | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41873211 | Derived | Gupta R, Kumar R, Kumar N, Singh P. Reimagining Brain Drug Delivery: Mechanistic and Translational Advances in Carbon Nanotube Nanomedicine. J Appl Toxicol. 2026 Jul;46(7):2250-2274. doi: 10.1002/jat.70154. Epub 2026 Mar 24. |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| D020734 | Parkinsonian Disorders |
| ID | Term |
|---|---|
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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Exhaled breath
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |