NI-0801 in Allergic Contact Dermatitis

A Proof-of-Principle Study Investigating the Effect of Single Doses of NI-0801 on Nickel Induced Contact Dermatitis

The purpose of the study is to assess the effect of a single dose of NI-0801 on the severity of nickel-induced allergic contact dermatitis.

Inclusion Criteria:

• Aged ≥ 18 and ≤ 70 years
• Either male or a female lacking childbearing potential
• Previously documented nickel allergy

Exclusion Criteria:

• Any medical condition that, in the opinion of the investigator, would interfere with safe completion of the trial or that would prevent subjects from providing informed consent.
• Known or previous diagnosis of malignancy
• Known current active tuberculosis or a history of active TB within 12 months of screening
• Known infection with HIV, Hepatitis B or C