Evaluation of Oxygen Therapy Delivery Systems in Hypoxemic Acute Respiratory Failure

Evaluation of Oxygen Therapy Delivery Systems in Hypoxemic Acute Respiratory Failure

The main objective of this study is to evaluate the efficiency of the oxygen therapy delivery system Optiflow® compared to 2 others standard oxygen therapy delivery systems (Ospal®, non invasive ventilation).12 immunocompetent patients will compare the successive use of oxygen therapy delivery systems Optiflow®/Ospal® and 12 immunodeficient patients will compare the successive use of systems Optiflow®/Non invasive ventilation.

Inclusion Criteria:

• Patient hospitalized in the intensive care unit of Nantes University Hospital
• Signed informed consent
• Patient with not hypercapnic acute hypoxemic respiratory failure
• Immunocompetent and immunodeficient patient

Exclusion Criteria:

• Age < 18 years
• Pregnancy
• Contra-indication to non invasive ventilation
• Allergy to xylocaine
• Coagulation troubles
• Tracheotomized patient
• Urgent indication to intubation
• Hypercapnic acute respiratory failure
• Acute pulmonary edema
• Face or nose malformation