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| Name | Class |
|---|---|
| URC-CIC Paris Descartes Necker Cochin | OTHER |
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This study aims at evaluating spinal cord structure using diffusion tensor imaging in patients with cervical spondylosis.
Diffusion tensor imaging (DTI) of the cervical spinal cord will be performed in patients with cervical spondylosis with varying degrees of symptoms and in healthy control subjects. Fibre tracking of main spinal tracts will be performed. Regions of interest will also be identified. Diffusion parameters will be extracted. This will allow quantification of degree of damage in of the spinal cord. The findings will be related to motor function measures and comprehensive clinical tests of sensory and motor function.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Healty volunteers | Active Comparator |
| |
| Patients | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| DTI - Diffusor Tensor Imaging | Device | Radiology intervention |
|
| Measure | Description | Time Frame |
|---|---|---|
| DTI parameters in cervical spinal cord | 3 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical data, i.e., Muscle testing, sensory testing, reflexes, spasticity, and Motor function (dexterity test), grip strength | Clinical data, i.e., Muscle testing, sensory testing, reflexes, spasticity Motor function (dexterity test), grip strength | 3 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Antoine FEYDY, PhD | Assistance Publique - Hôpitaux de Paris | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cochin Hospital, Radiology B | Paris | Île-de-France Region | 75014 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26123409 | Result | Lindberg PG, Sanchez K, Ozcan F, Rannou F, Poiraudeau S, Feydy A, Maier MA. Correlation of force control with regional spinal DTI in patients with cervical spondylosis without signs of spinal cord injury on conventional MRI. Eur Radiol. 2016 Mar;26(3):733-42. doi: 10.1007/s00330-015-3876-z. Epub 2015 Jun 27. |
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| ID | Term |
|---|---|
| D055009 | Spondylosis |
| D013118 | Spinal Cord Diseases |
| ID | Term |
|---|---|
| D013122 | Spinal Diseases |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D002493 | Central Nervous System Diseases |
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| D009422 |
| Nervous System Diseases |