Safety and Efficacy of Bimatoprost/Timolol Fixed Combination Versus Latanoprost in Patients With Open-Angle Glaucoma Who Have Never Been Treated

This study will evaluate the safety and efficacy of bimatoprost/timolol fixed combination (GANfort®) versus latanoprost (Xalatan®) in patients with open-angle glaucoma who have never been previously treated and are at high risk for progression.

Inclusion Criteria:

• Diagnosis of primary open-angle glaucoma that has never been treated
• Visual Acuity 20/60 or better in each eye

Exclusion Criteria:

• Eye surgery within 3 months
• Any refractive eye surgery
• Contraindication to beta-adrenoceptor antagonist therapy (eg, chronic obstructive pulmonary disease [COPD], bronchial asthma, sinus bradycardia, heart block, history of severe myocardial infarction [heart attack])
• Eye inflammation or eye infection within 3 months
• Eye trauma within 6 months
• Oral, injectable, or topical ophthalmic steroids within 21 days or anticipated use during study