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| ID | Type | Description | Link |
|---|---|---|---|
| 30901234 | Other Grant/Funding Number | Nature Science Foundation of China |
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The purpose of this study is to determine whether HIFU has superiority over traditional surgery on satisfaction and adverse impact.
Uterine fibroids (leiomyomas) are common in reproductive aged women. Patients are seeking new ways to treat symptomatic uterine fibroids that allow them to avoid surgery. High intensity focused ultrasound therapy (HIFU) is a novel non-invasive method for uterine fibroid. Preliminary clinical studies proved HIFU ablation is a safe and effective technology. However, it is not clear whether HIFU has superiority over traditional surgery on satisfaction and adverse impact.The study is to confirm these questions.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High intensity focused ultrasound | Procedure | The term 'high intensity focused ultrasound' means using ultrasound to causes coagulation necrosis to destroy the targeted tissue, in this case, uterine fibroids. |
|
| Measure | Description | Time Frame |
|---|---|---|
| The quality of life, adverse events | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Fibroid volume ablated | Detection of serum markers of trauma, The change of immunological function,Procedure duration, Time to return to normal activity ,Recurrence, Reintevention rate and Pregnancy outcome, Female reproductive function, Sexual function and psychological change | any time |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| LD Tang, PhD | the first affiliated Chongqing University Hospital, Dept of Obstetrics and Gynecolog | Study Chair |
| Z B wang, PhD | Biomedical Engineering Department of Chongqing Medical University | Study Director |
| Wen-Zhi Chen, MD | Clinical Center for Tumor Therapy, the 2nd Hospital of Chongqing Medical University | Principal Investigator |
| Jin-Yun Chen, PhD | Biomedical Engineering Department of Chongqing Medical University | Principal Investigator |
| Min Zhou, PhD | The first affiliated Chongqing University Hospital, Dept of Obstetrics and Gynecology | Principal Investigator |
| Juan Qin, PhD | Biomedical Engineering Department, Chongqing Medical University | Principal Investigator |
| Xiaoyan Wang, PhD | The first affiliated Chongqing University Hospital, Dept of Obstetrics and Gynecology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The 1st Hospital of Chongqing Medical University | Recruiting | Chongqing | Chongqing Municipality | 400000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23564052 | Derived | Wang X, Qin J, Wang L, Chen J, Chen W, Tang L. Effect of high-intensity focused ultrasound on sexual function in the treatment of uterine fibroids: comparison to conventional myomectomy. Arch Gynecol Obstet. 2013 Oct;288(4):851-8. doi: 10.1007/s00404-013-2775-2. Epub 2013 Apr 7. |
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| ID | Term |
|---|---|
| D007889 | Leiomyoma |
| ID | Term |
|---|---|
| D009379 | Neoplasms, Muscle Tissue |
| D018204 | Neoplasms, Connective and Soft Tissue |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D063186 | Uterine Myomectomy |
| ID | Term |
|---|---|
| D013509 | Gynecologic Surgical Procedures |
| D013519 | Urogenital Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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