Safety and Efficacy Study of DE-110 Ophthalmic Suspension for the Treatment of Dry Eye Disease

A Phase II, Prospective, Randomized, Observer-masked, Parallel-group, Multi-center Study Assessing the Safety and Efficacy of Two Concentrations Compared to Placebo for the Treatment of Dry Eye Disease

Investigate the Safety and Efficacy of Two Concentrations of DE-110 Compared to Placebo for the Treatment of Dry Eye Disease

Inclusion Criteria:

• Confirmed diagnosis of dry eye
• Not wear contact lenses during study
• 18 years or older
• Understand and provide written consent
• Negative pregnancy test and use acceptable method of contraception

Exclusion Criteria:

• Use of any topical ocular medication
• Any type of ocular surgery
• Diagnosis of on-going ocular infection and/or allergic conjunctivitis
• Uncontrolled systemic conditions/lid abnormalities
• Corneal transplants
• Females who are pregnant, nursing or planning a pregnancy
• Participation in another drug trial concurrently or within 30 days prior to study