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Prognostic impact of AR vs NAR
Whether anatomical is better than non anatomical resection for HCC is still debated. This prospective randomized study aimed to address which approach is better in terms of patients prognosis.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Anatomical resection | Experimental |
| |
| Non-anatomical resection | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| anatomical liver resection | Procedure | anatomical liver resection by means of IOUS-finger compression |
|
| Measure | Description | Time Frame |
|---|---|---|
| the prognostic impact of anatomical resection by means of intraoperative ultrasound (IOUS) guided vessel compression versus nonanatomical resection in terms of disease free and overall survival | 5-years |
| Measure | Description | Time Frame |
|---|---|---|
| the impact of anatomical resection versus non-anatomical resection in terms of postoperative mortality and morbility | 30 and 90 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Guido Torzilli, MD, PhD | Contact | +39 02 8224 | 4083 | guido.torzilli@unimi.it |
| Name | Affiliation | Role |
|---|---|---|
| Guido Torzilli, MD, PhD | IRCCS Istituto Clinico Humanitas, Milan, Italy | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| IRCCS Istituto Clinico Humanitas | Rozzano | Milan | 20089 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 16041216 | Background | Hasegawa K, Kokudo N, Imamura H, Matsuyama Y, Aoki T, Minagawa M, Sano K, Sugawara Y, Takayama T, Makuuchi M. Prognostic impact of anatomic resection for hepatocellular carcinoma. Ann Surg. 2005 Aug;242(2):252-9. doi: 10.1097/01.sla.0000171307.37401.db. | |
| 19838106 | Background | Torzilli G, Procopio F, Cimino M, Del Fabbro D, Palmisano A, Donadon M, Montorsi M. Anatomical segmental and subsegmental resection of the liver for hepatocellular carcinoma: a new approach by means of ultrasound-guided vessel compression. Ann Surg. 2010 Feb;251(2):229-35. doi: 10.1097/SLA.0b013e3181b7fdcd. |
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| Non-anatomical liver resection | Procedure | non-anatomical liver resection |
|
| 14625736 | Background | Torzilli G, Makuuchi M. Ultrasound-guided finger compression in liver subsegmentectomy for hepatocellular carcinoma. Surg Endosc. 2004 Jan;18(1):136-9. doi: 10.1007/s00464-003-9024-x. Epub 2003 Nov 21. |