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| ID | Type | Description | Link |
|---|---|---|---|
| 11710 | Other Identifier | DAIDS ID: 11710 | |
| UM1AI068619 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Allergy and Infectious Diseases (NIAID) | NIH |
| National Institute of Mental Health (NIMH) | NIH |
| National Institutes of Health (NIH) | NIH |
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Cash transfers to young women for staying in school and its effect on acquiring HIV
The overall purpose of this study is to determine whether providing cash transfers to young women and their household, conditional on school attendance, reduces young women's risk of acquiring Human Immunodeficiency Virus (HIV). The overall goal of the Conditional Cash Transfer (CCT) intervention is to reduce structural barriers to education with the goal of increasing school attendance of young women, thereby decreasing their HIV risk.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A--Monthly cash transfers | Other | Monthly cash transfer payments |
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| B--No cash transfers | Other | No cash transfers. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| monthly cash transfer payments for attending school | Behavioral | In the intervention, young women and their households will be randomized in 1:1 ratio to receive monthly cash transfer payments, conditional on the young woman attending school, or to the control arm. Young women will be recruited at the beginning of grades 8 through 11 in the first year of the study. |
| Measure | Description | Time Frame |
|---|---|---|
| HIV Incidence | To determine whether young women who are randomized to receive CCTs conditional on school attendance have a lower incidence of HIV infection over time compared to young women who are not randomized to receive cash transfers. | 4 years |
| Measure | Description | Time Frame |
|---|---|---|
| HSV-2 incidence | To determine whether young women who are randomized to receive CCTs conditional on school attendance have a lower incidence of Herpes Simplex Virus type 2 (HSV-2) infections over time compared to young women who are not randomized to receive cash transfers. | 4 years |
| HSV Incidence |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Audrey Pettifor | University of North Carolina | Study Chair |
| Xavier Gomez-Olive | Wits Rural Public Health and Health Transitions Research Unit | Principal Investigator |
| Kathleen Kahn | University of Witwatersrand, South Africa | Principal Investigator |
| Catherine McPhail | Reproductive Health & HIV Research Unit, University of Witwatersrand | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Agincourt | Acornhoek | South Africa |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37023659 | Derived | Rosenberg M, Beidelman E, Chen X, Canning D, Kobayashi L, Kahn K, Pettifor A, Kabudula CW. The impact of a randomized cash transfer intervention on mortality of adult household members in rural South Africa, 2011-2022. Soc Sci Med. 2023 May;324:115883. doi: 10.1016/j.socscimed.2023.115883. Epub 2023 Mar 31. | |
| 35790334 | Derived | Jayaweera RT, Goin D, Twine R, Neilands TB, Wagner RG, Lippman SA, Kahn K, Pettifor A, Ahern J. Associations between WASH-related violence and depressive symptoms in adolescent girls and young women in South Africa (HPTN 068): a cross-sectional analysis. BMJ Open. 2022 Jul 5;12(7):e061032. doi: 10.1136/bmjopen-2022-061032. |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_ICF | Yes | No | Yes | Study Protocol and Informed Consent Form | Jun 2, 2016 | Mar 20, 2025 | Prot_ICF_000.pdf |
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| B--No cash transfers | Behavioral | No monthly cash transfers |
|
To determine whether young women who receive the CCTs report less unprotected sex, fewer number of sexual partners, younger male partners, an older age of coital debut, a lower incidence of self-reported pregnancy, and greater school attendance compared to young women who do not receive the cash transfers. |
| 4 years |
| 32061464 | Derived | DeLong SM, Powers KA, Pence BW, Maman S, Dunkle KL, Selin A, Twine R, Wagner RG, Gomez-Olive FX, MacPhail C, Kahn K, Pettifor A. Longitudinal Trajectories of Physical Intimate Partner Violence Among Adolescent Girls in Rural South Africa: Findings From HPTN 068. J Adolesc Health. 2020 Jul;67(1):69-75. doi: 10.1016/j.jadohealth.2019.12.016. Epub 2020 Feb 13. |
| 28697762 | Derived | MacPhail C, Khoza N, Selin A, Julien A, Twine R, Wagner RG, Gomez-Olive X, Kahn K, Wang J, Pettifor A. Cash transfers for HIV prevention: what do young women spend it on? Mixed methods findings from HPTN 068. BMC Public Health. 2017 Jul 11;18(1):10. doi: 10.1186/s12889-017-4513-3. |
| 27815148 | Derived | Pettifor A, MacPhail C, Hughes JP, Selin A, Wang J, Gomez-Olive FX, Eshleman SH, Wagner RG, Mabuza W, Khoza N, Suchindran C, Mokoena I, Twine R, Andrew P, Townley E, Laeyendecker O, Agyei Y, Tollman S, Kahn K. The effect of a conditional cash transfer on HIV incidence in young women in rural South Africa (HPTN 068): a phase 3, randomised controlled trial. Lancet Glob Health. 2016 Dec;4(12):e978-e988. doi: 10.1016/S2214-109X(16)30253-4. Epub 2016 Nov 1. |