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The purpose of this study is to evaluate the blood loss in induced vaginal delivery by misoprostol and caesarians section with induction attempt.
Methods: it was a study achieved with 101 pregnant women with indication to induced delivery labor that were evaluated by the hemoglobin dosage pre and post delivery for estimate the blood loss at delivery. Patients were submitted to transabdominal obstetric ultrasound and basal cardiotocography. Procedures were taken for induced labor delivery with misoprostol 25mcg, by vaginal rout. The pills were administered each 6 hours in a maximum number of six. The control group was formed by 30 patients that began an spontaneously labor and 30 patients that achieved caesarians electively. The study of hemoglobin before and after delivery was evaluated through ANOVA to repeated measures, where it was verified the time effect (pre and post delivery) and the effect of the group (with and without use of misoprostol).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| spontaneous vaginal deliveries | Placebo Comparator |
| |
| elective caesarians | Placebo Comparator |
| |
| induced vaginal delivery by misoprostol | Experimental |
| |
| caesarians section with induction attempt | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Misoprostol | Drug | Procedures were taken for induced labor delivery with misoprostol 25mcg, by vaginal rout. The pills were administered each 6 hours in a maximum number of six. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Vaginal delivery | Procedures were taken for induced labor delivery with misoprostol 25mcg, by vaginal rout. The pills were administered each 6 hours in a maximum number of six. | 54 hours after the first pills |
| Measure | Description | Time Frame |
|---|---|---|
| blood loss | To evaluate the blood loss in spontaneous vaginal deliveries and elective caesarians through the hemoglobin dosage pre and post delivery. | 24 hours after delivery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Paulo César Praciano de Sousa, Mestre | Maternidade Escola Assis Chateaubriand | Principal Investigator |
| Francisco Edson de Lucena Feitosa, Doutor | Maternidade Escola Assis Chateaubriand | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Maternidade-Escola Assis Chateaubriand | Fortaleza | Ceará | 60430-270 | Brazil |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19187376 | Result | ElSedeek MSh, Awad EE, ElSebaey SM. Evaluation of postpartum blood loss after misoprostol-induced labour. BJOG. 2009 Feb;116(3):431-5. doi: 10.1111/j.1471-0528.2008.02054.x. |
| Label | URL |
|---|---|
| site of Maternidade-Escola Assis Chateaubriand | View source |
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| ID | Term |
|---|---|
| D016595 | Misoprostol |
| ID | Term |
|---|---|
| D011459 | Prostaglandins E, Synthetic |
| D011465 | Prostaglandins, Synthetic |
| D011453 | Prostaglandins |
| D015777 | Eicosanoids |
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|
| D005231 |
| Fatty Acids, Unsaturated |
| D005227 | Fatty Acids |
| D008055 | Lipids |
| D012898 | Autacoids |
| D018836 | Inflammation Mediators |
| D001685 | Biological Factors |