This study is to evaluate pharmacokinetic-pharmacodynamic property of C3G after administration of Mulberry fruit extract to 12 healthy Korean volunteers. Plasma concentration of C3G and the antioxidative markers such as total antioxidative capacity and attack of free oxygen radical will be measured.

Additional objective is to investigate the multiple dose (2 weeks) safety of daily 1000mg Mulberry fruit extract.

This study, as an exploratory trial, does not required statistical hypothesis.

Inclusion Criteria:

• Body weight >55 kg for male, >45 kg for female (within 80-120% of Ideal body weight)
• Give written informed consent and voluntarily decide participation

Exclusion Criteria:

• Acute or chronic disease symptom on screening
• Existing active and clinically significant disease involving more than one organ system
• Known allergy to Mulberry or other berries
• Positive drug or alcohol screening
• Smokers of 10 or more cigarettes per day
• Participation in a clinical trial during last 2 month prior to the start of the study
• Pregnancy