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| ID | Type | Description | Link |
|---|---|---|---|
| DOJ-2009-D1BX0299 | Other Grant/Funding Number | National Institute of Justice, Department of Justice |
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| Name | Class |
|---|---|
| University of Pennsylvania | OTHER |
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The study will compare the efficacy of Trauma Affect Regulation: Guide for Education and Therapy (TARGET) vs. the best validated psychotherapy for adults with posttraumatic stress disorder (PTSD), Prolonged Exposure (PE). Male military personnel and veterans suffering with PTSD and problems with anger after returning from military service in Afghanistan (Operation Emerging Freedom, OEF) and/or Iraq (Operation Iraqi Freedom, OIF) will be participants. The goal is to determine if a present-centered psychotherapy that teaches skills for emotion regulation and does not require re-telling of traumatic memories is as efficacious as the trauma memory-focused PE psychotherapy.
The study is based on a theoretical and clinical model that involves a series of associated risks that are set in motion by exposure to military-related traumatic stressors in Iraq or Afghanistan. Trauma exposure places personnel at risk for PTSD, which in turn increases their risk of problems with anger and hostility, emotion dysregulation and experiential avoidance, and ultimately with alcohol abuse and aggression. The two types of treatments being compared, TARGET (Trauma Affect Regulation: Guide for Education and Therapy) and PE (Prolonged Exposure), are both designed to directly reduce PTSD severity by reducing emotion dysregulation (TARGET) and experiential avoidance (PE), and therefore are hypothesized to reduce the risk and severity of alcohol abuse and aggression- and thereby to reduce associated legal and societal costs.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| TARGET | Experimental | Affect regulation psychotherapy for PTSD |
|
| Prolonged Exposure | Active Comparator | Cognitive behavioral therapy for PTSD with trauma memory exposure |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| TARGET (Trauma Affect Regulation) | Behavioral | TARGET teaches a skill sequence for affect regulation and social/interpersonal information processing. |
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| Measure | Description | Time Frame |
|---|---|---|
| Severity of PTSD symptoms | Clinician Administered PTSD Scale Ordinal Scores Posttraumatic Cognitions Inventory Trauma Memory Questionnaire Interpretation of PTSD Symptoms Scale | Post-therapy |
| Measure | Description | Time Frame |
|---|---|---|
| Anger/aggression problems | State-Trait Anger Expression Inventory Brief Symptom Inventory | Post-therapy |
| Emotion Regulation | Negative Mood Regulation scale Difficulty with Emotion Regulation Scale Acceptance and Action Questionnaire |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Julian Ford, Ph.D. | UConn Health | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Connecticut Health Center | Farmington | Connecticut | 06030-1410 | United States |
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| ID | Term |
|---|---|
| D013313 | Stress Disorders, Post-Traumatic |
| D000374 | Aggression |
| ID | Term |
|---|---|
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |
| D001523 | Mental Disorders |
| D000096762 | Aberrant Motor Behavior in Dementia |
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| Prolonged Exposure | Behavioral | Cognitive behavior therapy with trauma memory exposure |
|
| Post-therapy |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
| D012919 | Social Behavior |