The study was designed to assess the effect of food on the extent and rate of absorption of Dihydroartemisinin (DHA) and Piperaquine Phosphate (PQP) administered as a fixed dose combination (Eurartesim™).

Inclusion Criteria:

• Caucasian healthy males aged between 18 and 50 years(inclusive).
• Body Mass Index (BMI) between 19.0 kg/m2 and 27.0 kg/m2 inclusive, with a minimum body weight of 75 kg.
• Agreed to use two approved methods of contraception from Screening and until 90 days after administration of the study drug
• Had given written informed consent to participate in this study in accordance with local regulations.

Exclusion Criteria:

• Had received or was anticipated to receive a prescription medication within 14 days prior to the start of dosing or an over-the-counter medicine 48 hours prior to the start of dosing.
• Abnormal laboratory test results deemed clinically significant by the Medical Officer.
• Positive urine drug test (e.g. opiates and cannabinoids) or alcohol breath test.
• History of significant drug allergies or significant allergic reaction.
• Receipt of blood or blood products, or loss or donation of 450 mL or more of blood within 90 days before the first dose administration.