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| Name | Class |
|---|---|
| Sahlgrenska University Hospital | OTHER |
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The purpose with this study was to compare blood loss and women's experience of afterpains during the third stage when handled with active or expectant management of the third stage of labour.
Hypothesis 1. To detect a 5% difference (15% vs 10%) in blood loss >1000 mL between the two groups with 80% power (α=0.05), at least 726 subjects were required in each group.
Hypothesis 2. Afterpains are more pronounced in active compared to expectant management during the third stage of labour
Management of the third stage of labour has been focus for investigation during decades and active management of the third stage of labour (AMTSL)has been recommended in all women giving birth vaginally at hospitals. In Sweden the recommendation has been to give an injection of oxytocin immediately after birth of the neonate but not the entire AMTSL procedure.
Women in labour were asked to participate voluntarily when entering the hospital and after acceptance they were randomised to either active or expectant management of the third stage of labour(EMTSL).
AMTSL included:
EMTSL included:
All blood was measured by weighing bed pads and sanitary towels up to two hours postpartum Assessment of afterpains was performed by a Visual Analogue Scale (VAS) and the Pain-o-meter (POM-WDS) two hours after the delivery of placenta, and the day after childbirth.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| oxytocin | Active Comparator | early cord clamping, administration of oxytocin 10 IU i.v, controlled cord traction, uterine massage after placenta expulsion |
|
| saline solution | Placebo Comparator | early cord clamping, wait for signs of placenta detachment, encourage the woman to push out placenta by her own effort, uterine massage after placenta expulsion |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| active management of the third stage of labor | Procedure | early cord clamping, administration of oxytocin 10 IU, controlled cord traction, uterine massage after placenta expulsion |
| Measure | Description | Time Frame |
|---|---|---|
| blood loss | All blood was collected and measured from delivery of the infant and two hours after. | blood loss measured up to two hours post partum |
| Measure | Description | Time Frame |
|---|---|---|
| afterpains | Women assessed their afterpains at two hours and the day after delivery | at two hours postpartum and the day after delivery |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| elisabeth jangsten | Sahlgrenska academy, University of Gothenburg | Principal Investigator |
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| ID | Term |
|---|---|
| D006473 | Postpartum Hemorrhage |
| ID | Term |
|---|---|
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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|
| expectant management of the third stage of labor | Procedure | early cord clamping, administer saline solution 2 mL i.v,wait for signs of placenta detachment, encourage the woman to push ot placenta by her own effort, uterine massage after placenta expulsion |
|
|
| D011644 | Puerperal Disorders |
| D014592 | Uterine Hemorrhage |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |