Endoplasmic Reticulum Stress in Chronic Respiratory Diseases | NCT01211015

Studies
Endoplasmic Reticulum Stress in Chronic Respiratory Diseases

NCT01211015

Sponsor

Chonbuk National University

Status

Unknown status

Last Update Posted

Sep 29, 2010Estimated

Enrollment

50Estimated

Phase

Not provided

Conditions

ER Stress,
Chronic Airway Disorders,
Lung Cancer,
Interstitial Lung Diseases

Interventions

Not provided

Countries

South Korea

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Sep 2010

Overall Recruitment Status or Expanded Access Status

Unknown status

Last Known Status

Recruiting

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jul 2010

Primary Completion Date

Not provided

Completion Date

Not provided

First Submitted Date

Sep 28, 2010

First Submission Date that Met QC Criteria

Sep 28, 2010

First Posted Date

Sep 29, 2010Estimated

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Sep 28, 2010

Last Update Posted Date

Sep 29, 2010Estimated

Description Module

Brief Summary

Aim: To investigate whether ER stress is implicated in the pathogenesis of various pulmonary disorders

Measurement:

Unfolded protein responses (UPRs) in blood (PBMCs)of patients
1. CHOP
2. GRP 78 and so on
Unfolded protein responses (UPRs) in blood (PBMCs)of healthy controls
1. CHOP
2. GRP 78 and so on

Detailed Description

Not provided

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Not provided

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

Retention

Enrollment

50Estimated

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Control group		healthy control group
Disease group		asthma, COPD, ILD, lung malignancy

Interventions

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

> 18 yrs
Definitive diagnosis as chronic pulmonary diseases by physician

Exclusion Criteria:

Any other chronic medical illness such as DM, HTN, and other malignancy

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

18 Years

Maximum Age

80 Years

Standard Ages

AdultOlder Adult

Study Population

Control group
- healthy control (volunteer)
Disease group
- chronic pulmonary lung diseases including asthma, COPD, ILD, and lung cancer

Sampling Method

Probability Sample

Contacts/Locations Module

Central Contacts

Name	Role	Phone	Extension	Email
Yong Chul Lee, MD, phD	Contact	82-63-250-1664	1664	leeyc@chonbuk.ac.kr

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Chonbuk National University Hospital	Recruiting	Jeonju	Jeollabuk-do	561-180	South Korea

Condition Browse Module

MeSH Terms

ID	Term
D008175	Lung Neoplasms
D017563	Lung Diseases, Interstitial

Ancestor Terms

ID	Term
D012142	Respiratory Tract Neoplasms
D013899	Thoracic Neoplasms
D009371	Neoplasms by Site
D009369	Neoplasms

Browse Leaves

Not provided

Browse Branches

Not provided