Study of Blood Samples From Patients With Ewing Sarcoma and Their Relatives

GENEWING - A Genome Wide Association Study in Ewing Sarcoma

RATIONALE: Studying samples of blood in the laboratory from patients with cancer and their relatives may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.

PURPOSE: This research study is looking at blood samples collected from patients with Ewing sarcoma and their relatives.

OBJECTIVES:

• To identify and characterize a genetic susceptibility factor to Ewing's sarcoma by performing a Genome-Wide Association Study with as many as possible Ewing sarcoma patients.

OUTLINE: This is a multicenter study.

Blood samples are collected from patients and their relatives. Blood DNA samples are analyzed for susceptibility genes of Ewing Sarcoma.

DISEASE CHARACTERISTICS:

• Patients with Ewing sarcoma
• Relatives of Ewing sarcoma patients

PATIENT CHARACTERISTICS:

• Patients with a fusion genes specific of Ewing Sarcoma

PRIOR CONCURRENT THERAPY:

• Not applicable