To date, there is a lack of consensus concerning the optimal timing for removal of the urethral catheter, its related complications, the effectiveness in prophylactic drug use to reduce complication, and the patient reported outcomes (quality of life) after robot-assisted laparoscopic prostatectomy (RALP). The purpose of this study is to determine the impact of tamsulosin on voiding patterns following early urethral catheter removal after RALP for prostate cancer.

Inclusion Criteria:

• Patients must have localized or locally advanced prostate cancer
• Patients must receive robot assisted laparoscopic radical prostatectomy
• Patients must be able to provide written informed consent

Exclusion Criteria:

• Patients must not have a history of treatment with alpha blockers within 4 weeks
• Patients must not have previously undergone transurethral resection, laser therapy, or other surgery of the prostate
• Patients must not have previously been diagnosed with neurogenic bladder
• Patients must not have hypersensitivity to trial drug or other alpha-blockers
• Patients must not have the participation of other clinical trial within the past 3 months