The Effects of Moviprep With Simethicone on Colonic Bubbles

The Effects of Moviprep With Simethicone on Colonic Bubbles

The purpose of this study is to determine whether the administration of PEG along with simethicone will reduce the incidence of colonic bubbles that interfere with polyp detection.

evaluating if simethicone is better than placebo at decreasing gas in the colon at time of colonoscopy so that it is easier for the endoscopist to see polyps

Inclusion Criteria:

-Elective outpatients undergoing colonoscopy using split dose PEG-ELS with sodium ascorbate and ascorbic acid

Exclusion Criteria:

• Unable or unwilling to give informed consent
• Age < 18 years
• Pregnant
• Breast feeding
• Established or suspected gastroparesis
• Pseudo-obstruction - established or suspected
• Severe constipation (< 1 BM a week)
• Bowel obstruction
• Greater than 50% resection of colon
• Chronic nausea or vomiting
• Consumed > 100% standard dose of PEG-ELS (i.e. more than 2L)
• G6PD deficiency
• PEG allergy
• Significant psychiatric illness