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It was well known that long term intubation caused a various kind of abnormal presentations of dysphagia such as the increased aspiration risk, the decreased gag reflex, mucosal pathology, the airway stenosis and so on. It was thought that the freezing and impaired proprioception to be developed as a result of dis-use around the pharynx and the larynx while intubation was one of the reason.
Preemptive swallowing manual stimulation applied on the oral cavity to avoid the vicious cycle of dis-use was reported to improve dysphagia after extubation.
Neuromuscular electrical stimulation have been utilized for a wide variety of dysphagia of multiple causes of neuro-muscular disorder.
Supposing that preemptive transcutaneous neuromuscular electrical stimulation to be delivered to the muscles of being involved in swallowing could decrease the degree of dis-use during intubation so that it could reduce the occurence and severity of dysphagia developed after extubation, the investigators plan to perform randomized prospective double blind placebo controlled clinical interventional study.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transcutaneous neuro-muscular electrical stimulation | Procedure | Neuro-muscular electrical stimulation with two pairs of surface electrodes was applied to submental area. One paired electrodes to be placed horizontally was attached on the anterior half of area between mandible and hyoid bone. The other was affixed to posterior half of the same area far laterally. Bipolar electrical stimulation with pulse rate of 80-Hz, duration of 700 µs and intensity to evoke visible muscle contraction was performed for 60 minutes a day until one day before extubation. |
|
| Measure | Description | Time Frame |
|---|---|---|
| oro-pharyngeal swallowing efficiency | oro-pharyngeal swallowing efficiency was calculated by using the data derived from videofluoroscopic swallowing study | as soon as patient could tolerate videofluoroscopic swallowing study after extubation; average of 5 days |
| Measure | Description | Time Frame |
|---|---|---|
| oral transit time | oral transit time was measured through videofluoroscopic swallowing study | as soon as patient could tolerate videofluoroscopic swallowing study after extubation; average of 5 days |
| pharyngeal transit time |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Chang Ho Hwang, M.D. | Ulsan University Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ulsan University Hospital | Ulsan | 682-714 | South Korea |
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| ID | Term |
|---|---|
| D003680 | Deglutition Disorders |
| ID | Term |
|---|---|
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
| D010608 | Pharyngeal Diseases |
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pharyngeal transit time was measured through videofluoroscopic swallowing study
| as soon as patient could tolerate videofluoroscopic swallowing study after extubation; average of 5 days |
| oro-pharyngeal transit time | oro-pharyneal transit time was calculated by using the data derived from videofluoroscopic swallowing study | as soon as patient could tolerate videofluoroscopic swallowing study after extubation; average of 5 days |
| swallowed volume | swallowd volume was measured through videofluoroscopic swallowing study | as soon as patient could tolerate videofluoroscopic swallowing study after extubation; average of 5 days |
| aspiration volume | aspiration volume was measured through videofluoroscopic swallowing study | as soon as patient could tolerate videofluoroscopic swallowing study after extubation; average of 5 days |
| presence of aspiration | presence of aspiration was checked through videofluoroscopic swallowing study | as soon as patient could tolerate videofluoroscopic swallowing study after extubation; average of 5 days |
| presence of silent aspiration | presence of silent aspiration was checked through videofluoroscopic swallowing study | as soon as patient could tolerate videofluoroscopic swallowing study after extubation; average of 5 days |
| penetration-aspiration scale | penetration-aspiration scale was scored through videofluoroscopic swallowing study | as soon as patient could tolerate videofluoroscopic swallowing study after extubation; average of 5 days |
| D010038 | Otorhinolaryngologic Diseases |