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To evaluate the percentage of severe heart defect diagnosed with the use of color Doppler at a routine fetal scan in the second trimester of pregnancy
Almost all women in Norway have a routine ultrasound examination in the second trimester, however, the detection rate of heart defect are only around 50%. In this study we use color Doppler at three different levels in the fetal heart; the four chamber view, the outlet of the aorta on on the level of the great arteries.
All heart defects at delivery are recorded and compared with the ultrasound findings.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pregnant women | Pregnant females in the 2nd trimester. |
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| Measure | Description | Time Frame |
|---|---|---|
| Sensitivity of Color Doppler Examination to Detect Major Heart Defects During the Second Trimester of Pregnancy | The number of *fetuses with* heart defects detected by color Doppler in the second trimester was compared to the number of *fetuses with* major heart defects detected at birth. | 2nd trimester |
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Inclusion Criteria:
Exclusion Criteria:
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Pregnant women for routine examination in the 2nd trimester.
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| Name | Affiliation | Role |
|---|---|---|
| Claudia Heien, RN | Helse Stavanger HF | Principal Investigator |
| Torbjørn M. Eggebø, MD | Helse Stavanger HF | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Stavanger University Hospital | Stavanger | NO-4011 | Norway |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 7552797 | Background | Tegnander E, Eik-Nes SH, Johansen OJ, Linker DT. Prenatal detection of heart defects at the routine fetal examination at 18 weeks in a non-selected population. Ultrasound Obstet Gynecol. 1995 Jun;5(6):372-80. doi: 10.1046/j.1469-0705.1995.05060372.x. | |
| 12528169 | Background | Chaoui R, McEwing R. Three cross-sectional planes for fetal color Doppler echocardiography. Ultrasound Obstet Gynecol. 2003 Jan;21(1):81-93. doi: 10.1002/uog.5. |
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Data wil not be shared outside the research group. Results are published (see references).
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| ID | Title | Description |
|---|---|---|
| FG000 | Pregnant Women in Second Trimester | Pregnant females in the 2nd trimester. |
| Title | Milestones | Reasons Not Completed | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
The number of heart defects detected by color Doppler in the second trimester was compared to the number of major heart defects detected at birth to determine the sensitivity of the color Doppler examination to detect major heart defects in the second trimester.
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| ID | Title | Description |
|---|---|---|
| BG000 | Pregnant Women in Second Trimester | Pregnant females in the 2nd trimester. |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Continuous | Median |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Sensitivity of Color Doppler Examination to Detect Major Heart Defects During the Second Trimester of Pregnancy | The number of *fetuses with* heart defects detected by color Doppler in the second trimester was compared to the number of *fetuses with* major heart defects detected at birth. | Posted | Number | fetuses | 2nd trimester |
|
|
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Pregnant Women | Pregnant females in the 2nd trimester. |
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| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Torbjørn Moe Eggebø, phd | StavangerUH | 004792699433 | tme@lyse.net |
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| ID | Term |
|---|---|
| D006330 | Heart Defects, Congenital |
| ID | Term |
|---|---|
| D018376 | Cardiovascular Abnormalities |
| D002318 | Cardiovascular Diseases |
| D006331 | Heart Diseases |
| D000013 | Congenital Abnormalities |
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| 22685669 | Result | Eggebo TM, Heien C, Berget M, Ellingsen CL. Routine use of color Doppler in fetal heart scanning in a low-risk population. ISRN Obstet Gynecol. 2012;2012:496935. doi: 10.5402/2012/496935. Epub 2012 May 20. |
| years |
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| Sex: Female, Male | Count of Participants | Participants |
|
|
|
| 0 |
| 6,781 |
| 0 |
| 6,781 |
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| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |