The purpose of this study is to determine the prevalence of Fabry mutations in patients with left ventricular hypertrophy (moderate to severe), as measured by echocardiography.This study is a screening study

Inclusion Criteria:

• All patients over 18 years undergoing a routine echocardiography in the participating hospitals
• Both genders will be considered.
• Patients can be included if on 2D echocardiography the maximal septal wall thickness > 13 mm and/or the posterior wall thickness > 13 mm. The limit for inclusion is kept relatively low to detect early forms of Fabry cardiomyopathy.

patients with left ventricular hypertrophy