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The purpose of this study is to compare the results skin prick tests using simple blood lancet (Vitrex®) with DuoTips among mite-sensitized subjects.
We intend to compare results of skin prick tests by using simple blood lancet(Vitrex®) and DuoTips in terms of wheal size, variability, transfer of allergen and pain level, among mite-sensitive subjects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Mite-sensitized person |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Simple blood lancet | Device | Skin prick testing with blood lancet and DuoTip is performed on the back of mite-sensitized person. Allergen(Der p)is placed in 1st and 2nd row whereas histamine is placed in 3rd row. Allergen and normal saline are placed alternately in 4th row. Block randomization were allocated subjects into 2 groups; Group1:blood lancet is performed in 1st row and DuoTip in 2nd row. Group2:DuoTip is performed in 1st row and blood lancet in 2nd row. Blood lancet is applied in 3rd and 4th row in all subjects. A technician performed device applications and another technician who is blinded to device performed all readings. Pain was assessed on a scale from 0 to 10 with 0 being no pain and 10 being the worst imaginable pain |
| Measure | Description | Time Frame |
|---|---|---|
| Wheal and flare reaction to Der p results of skin prick test by simple blood lancet (Vitrex®) | To determine
| 15 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Determine transfer of allergen by simple blood lancet and Duotips. | To determine
| 15 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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Individuals who have positive skin prick testing to Der p 10,000 AU/ml (wheal size 3 mm at least)
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| Name | Affiliation | Role |
|---|---|---|
| Professor Pakit Vichyanond, MD | Siriraj Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Pediatrics, Siriraj hospital, Mahidol University | Bangkok | 10700 | Thailand |
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| ID | Term |
|---|---|
| D006967 | Hypersensitivity |
| ID | Term |
|---|---|
| D007154 | Immune System Diseases |
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