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The purpose of this study is to evaluate the acceptability and feasibility of an enhanced, individual-level counseling intervention for individuals in the acute and early phase of HIV infection aimed at reducing risk behaviors.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Enhanced counseling | Experimental | 5 intensive counseling sessions following acute HIV infection |
|
| Standard counseling | Active Comparator | Standard HIV counseling following acute HIV infection |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Standard counseling | Behavioral | Standard HIV counseling |
|
| Measure | Description | Time Frame |
|---|---|---|
| Proportion of participants in the experimental arm who receive the first four intervention sessions between enrollment and week 2 visit | Week 2 |
| Measure | Description | Time Frame |
|---|---|---|
| Number of self-reported unprotected sex acts | 6 months |
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Inclusion Criteria:
Be enrolled in CHAVI 001 Note: The inclusion and exclusion criteria for CHAVI 001 are provided below. The criteria will not be reassessed prior to enrollment in HPTN 062.
Inclusion Criteria from CHAVI 001
Exclusion Criteria:
Any prior or current use of antiretroviral therapy (ART). This does not apply to individuals screening for Group 1A. ART use for the prevention of perinatal transmission may be waived after prior consultation with the protocol team.
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| Name | Affiliation | Role |
|---|---|---|
| Amy Corneli, PhD | FHI 360 | Study Chair |
| Audrey Pettifor, PhD | FHI 360 | Study Chair |
| Francis Martinson, Md, PhD | Kamuzu Central Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kamuzu Central Hospital | Lilongwe | Malawi |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25962118 | Derived | Pettifor A, Corneli A, Kamanga G, McKenna K, Rosenberg NE, Yu X, Ou SS, Massa C, Wiyo P, Lynn D, Tharaldson J, Golin C, Hoffman I; HPTN 062 Study Protocol Team. HPTN 062: A Pilot Randomized Controlled Trial Exploring the Effect of a Motivational-Interviewing Intervention on Sexual Behavior among Individuals with Acute HIV Infection in Lilongwe, Malawi. PLoS One. 2015 May 11;10(5):e0124452. doi: 10.1371/journal.pone.0124452. eCollection 2015. |
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