Dual Source CT Angiography for Detection of Coronary Artery Stenoses

Multicenter Evaluation of Coronary Dual Source CT Angiography in Patients With Intermediate Risk of Coronary Artery Stenoses

The trial will investigate the accuracy of Dual Source CT coronary angiography to detect coronary artery stenoses in patients with chest pain who have, based on clinical criteria, an intermediate likelihood for the presence of coronary artery stenoses. No beta blockers will be used to lower the heart rate for the examination. The hypothesis is that Dual Source CT will allow the detection of vessels with at least one coronary artery stenosis with a sensitivity of more than 90%.

Inclusion Criteria:

• suspected coronary artery disease
• chest Pain
• intermediate likelihood of coronary stenoses
• planned invasive coronary angiography
• age 30 to 80 years

Exclusion Criteria:

• non sinus rhythm
• contrast allergy
• renal failure
• unstable clinical condition
• previous coronary revascularization
• calcium score exceeding 800
• inability to perform 10 second breathhold
• possible pregnancy
• metformin medication that cannot be interrupted
• inability to establish antecubital iv access