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The objectives of the proposed study are to assess the effect of walnut consumption on parameters of lipid metabolism, glucose metabolism, incretins and adipokines, endothelial function and blood pressure in healthy men and healthy postmenopausal women
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| walnut | Experimental | western type diet with 48 g walnut per day |
|
| control | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| walnut | Dietary Supplement | walnut consumption 48 g/d |
|
| Measure | Description | Time Frame |
|---|---|---|
| Fasting non-HDL-cholesterol | 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| area under the triglyceride curve (AUC-TG) | area under the plasma triglyceride concentration curve following a standardized oral fat challenge | 8 weeks |
| incremental area under the triglyceride curve (iAUC-TG) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Med Dept. 2 Grosshadern | Munich | 81377 | Germany |
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| ID | Term |
|---|---|
| C000624464 | PR-10 protein, walnut birch pollen |
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incremental area under the plasma triglyceride concentration curve following a standardized oral fat challenge
| 8 weeks |
| LDL-cholesterol | fasting plasma LDL-cholesterol concentration | 8 weeks |
| HDL-cholesterol | fasting plasma HDL-cholesterol concentration | 8 weeks |
| triglyceride | fasting plasma triglyceride concentration | 8 weeks |
| glucose | fasting plasma glucose concentration | 8 weeks |
| HOMA | 8 weeks |
| insulin | 8 weeks |
| HbA1c | 8 weeks |
| area under the glucose curve (AUC-glucose) | area under the plasma glucose concentration curve following a standardized oral challenge | 8 weeks |
| area under the insulin curve (AUC-insulin) | area under the plasma insulin concentration curve following a standardized oral challenge | 8 weeks |
| endothelial function | Postprandial (mixed meal challenge) endothelial function (flow mediated dilatation, flow-independent dilatation) | 8 weeks |