Study of Tocotrienol Absorption and Distribution Under Different Fat Status

Mechanism of Absorption and Distribution of Tocotrienols Under Different Food Status

Despite the emerging interest in tocotrienols, the absorption of tocotrienols in humans remains unclear especially with different fat diets.This study aimed at evaluating the absorption and distribution of tocotrienols in plasma and lipoproteins in associations with high and low fat diets. Different fat level will affect the absorption and distribution of tocotrienols

There is a possibility that the absorption and distribution of tocotrienols may occur differently compared with tocopherols, especially under different fat status

Inclusion Criteria:

• male aged 22-25
• body mass index 18.5 < X < 30 kg/m2
• plasma cholesterol < 5.2 mmol/L,
• TAG < 1.7 mmol/L

Exclusion Criteria:

• history of cardiovascular disease
• diabetic
• body mass index < 18.5 or > 30 kg/m2
• plasma cholesterol > 5.2 mmol/L,
• TAG > 1.7 mmol/L
• hypertension
• currently taking Vitamin E supplement
• current use of medication
• smoking.