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| Name | Class |
|---|---|
| University of Malaya | OTHER |
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Despite the emerging interest in tocotrienols, the absorption of tocotrienols in humans remains unclear especially with different fat diets.This study aimed at evaluating the absorption and distribution of tocotrienols in plasma and lipoproteins in associations with high and low fat diets. Different fat level will affect the absorption and distribution of tocotrienols
There is a possibility that the absorption and distribution of tocotrienols may occur differently compared with tocopherols, especially under different fat status
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High fat | Experimental | 500 mg of tocotrienol will be administered at single dose after consumption of high fat diet |
|
| Low fat | Experimental | 500 mg of tocotrienol will be administered at single dose after consumption of low fat diet |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Tocotrienol | Dietary Supplement | 500 mg of tocotrienol will be administered after consumption of high fat diet |
|
| Measure | Description | Time Frame |
|---|---|---|
| Difference in absorption and distribution of Tocoterienols during high fat and low fat meal by measuring the plasma, chylomicron, and HDL level of tocotrienol | 0, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 24 hours after tocotrienol administration and in take of designated meal |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Weng-Yew Wong, Bsc | Malaysia Palm Oil Board | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Malaysian Palm Oil Board | Bangi | Selangor | 43000 | Malaysia |
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| ID | Term |
|---|---|
| D024508 | Tocotrienols |
| ID | Term |
|---|---|
| D014810 | Vitamin E |
| D001578 | Benzopyrans |
| D011714 | Pyrans |
| D006573 | Heterocyclic Compounds, 1-Ring |
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| Tocotrienol | Dietary Supplement | 500 mg of tocotrienol will be administered after consumption of low fat diet |
|
| D006571 |
| Heterocyclic Compounds |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |