Cognitive-Behavior Therapy for Young Adults With Bipolar Disorder

Reducing High-Risk Behaviors Among Bipolar Patients Transitioning to Adulthood

The aim of the study is to develop and pilot test a cognitive-behavioral (CBT) intervention for young adults, ages 18-24 with bipolar disorder. The 14-week intervention focuses on improving management of bipolar disorder, reducing involvement in high-risk behaviors, and enhancing psychosocial functioning. The intervention also focuses on issues specific to transition-age youth. The study includes two phases: In phase 1, the intervention will be developed, refined, and openly piloted with several participants. In phase 2,the investigators will conduct a randomized clinical trial, in which 40 participants will be randomized either to receive the intervention right away, or to a 14-week waitlist condition. Participants will be evaluated at baseline, week 5, week 10, and week 14 of the study period, as well as at 3- and 6-month follow up, using measures of mood symptoms, high-risk behaviors, drug and alcohol use, and psychosocial functioning.

Inclusion Criteria:

• diagnosis of bipolar spectrum disorder (Bipolar I, Bipolar II, or Bipolar NOS Disorder)
• ages 18-24 years
• able to understand the nature of the study as well as potential risks and benefits
• in treatment with a physician or nurse-practitioner for their bipolar disorder, or willing to seek and obtain such treatment if needed.

Exclusion Criteria:

• concurrent cognitive-behavioral psychotherapy
• documented mental retardation
• pervasive developmental disorder
• current serious medical illness
• inability to participate in the intervention because of acuity of symptoms
• current drug or alcohol dependence (other than marijuana dependence)