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The purpose of the study is to compare a fish oil containing lipid emulsion against a medium-chain/long-chain triglyceride (MCT/LCT) lipid emulsion in terms of their efficacy and safety during postoperative parenteral nutrition.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 1 | Experimental | fish oil containing lipid emulsion |
|
| 2 | Active Comparator | MCT/LCT containing lipid emulsion |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| fish oil containing lipid emulsion | Drug | medium chain triglycerides, long chain triglycerides, omega-3 fatty acid containing triglycerides |
|
| Measure | Description | Time Frame |
|---|---|---|
| To investigate on the efficacy of fish oil on the nutrition status | Prealbumin as the primary endpoint variable | day 1 to day 6 |
| To investigate on the efficacy of fish oil on an inflammatory parameter | LTB5/LTB4 as a second primary endpoint | day 1 to day 6 |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of postoperative complications | 6 days | |
| Liver function | 6 days | |
| Coagulation parameters |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ning Li, Prof. MD. PhD. | Nanjing Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospitals | Beijing | 100730 | China | |||
| Nanjing Hospital |
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| ID | Term |
|---|---|
| D006963 | Hyperphagia |
| ID | Term |
|---|---|
| D012817 | Signs and Symptoms, Digestive |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| MCT/LCT containing lipid emulsion | Drug | medium chain triglycerides, long chain triglycerides |
|
| 6 days |
| Blood chemistry | 6 days |
| SIRS | 6 days |
| Nanjing |
| 210002 |
| China |