Sodium Bicarbonate for Prevention of Contrast-Induced Nephropathy

Hydration With Sodium Bicarbonate for Prevention of Contrast-Induced Nephropathy: A Multicenter Clinical Trial

The purpose of this study is to determine whether hydration with sodium bicarbonate is superior to hydration with saline to prevent contrast-induced nephropathy.

Inclusion Criteria:

• serum creatinine > 1.1 mg/dL
• glomerular filtration rate (GFR) < 50 mL/min

Exclusion Criteria:

• age < 18 years
• use of radiographic contrast media during the last 21 days
• history of dialysis
• cardiac insufficiency class III-IV
• emergency procedures