Effect of Bifidobacterium Lactis HN019 on Colonic Transit Time and Digestive Symptoms

A Three-Arm, Placebo Controlled, Double-Blind, Single Center Study to Evaluate the Impact of Probiotic Strain Bifidobacterium Lactis HN019 on Intestinal Well-Being, Colonic Transit Time and Digestive Discomfort

The purpose of this study was to investigate the dose response effect of Bifidobacterium lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms.

Inclusion Criteria:

• healthy males and females aged 25 to 65 years
• stool type 2-4 on the Bristol Stool Chart
• 1 to 3 bowel movements per week

Exclusion Criteria:

• use of any probiotic product intended to improve gastrointestinal function within the 2 weeks preceding study entry
• major chronic and uncontrolled systemic medical conditions
• severe gastrointestinal conditions known to prolong CTT
• lactose intolerance
• chronic diarrhea
• gastric bypass surgery or lap band insertion for weight loss
• regular laxative use
• pregnant or breast-feeding women