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Assess the role of a nicotine antagonist in helping patients presenting to hospital with acute coronary syndrome to stop smoking.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| active Chantix | Experimental | active drug to help smoking cessation |
|
| sugar pill | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Varenicline 100 mg by mouth twice daily | Drug | this is an active drug to help smoking cessation |
|
| Measure | Description | Time Frame |
|---|---|---|
| nicotine levels | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| recurrent myocardial ischemia | 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Newark Beth Israel Medical Center | Recruiting | Newark | New Jersey | 07112 | United States |
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| control | Drug | this is the placebo that will help us maintain a blinded study |
|
| ID | Term |
|---|---|
| D012907 | Smoking |
| D054058 | Acute Coronary Syndrome |
| D014029 | Tobacco Use Disorder |
| ID | Term |
|---|---|
| D001519 | Behavior |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
| D019966 | Substance-Related Disorders |
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D000068580 | Varenicline |
| ID | Term |
|---|---|
| D001552 | Benzazepines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006571 | Heterocyclic Compounds |
| D011810 | Quinoxalines |
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