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Irritable bowel syndrome (IBS) causes many symptoms, including abdominal pain, irregular bowel movements and bloating. It may be caused by loe degree inflammation of the intestine. The ingredients of coltect which contains green tea, selenium, and curcumin have been proven very safe and have anti inflammatory and anti oxidant activity. The aim of the study is to see whether the use of Coltect can improve symptoms in IBS patients.
The etiology of Irritable bowel syndrome is unknown but some evidence suggests it may be caused by a certain degree of inflammation, another theory is that intestinal flora has an influence on IBS. Coltect combines 3 ingredients: green tea, selenium and curcumin, all of which have been shown to have anti inflammatory and anti oxidant activity. the aim of the study is to investigate if use of coltect can improve symptoms in IBS patients
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| treatment with study drug | Active Comparator | patients receiving study drug for 4 weeks. 3 capsules a day of coltect |
|
| placebo | Placebo Comparator | patients receiving similar capsules but no active ingredients |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| coltect | Dietary Supplement | green tea 250 mg, selenium 100 micro gram, curcumin 500 mg |
|
| Measure | Description | Time Frame |
|---|---|---|
| improvement of IBS symptoms and quality of life | improvement of IBS symptoms and quality of life (QOL) assessed by IBS and QOL questionaires. | 10 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| change in bacterial stool flora | stool tests to investigate change in intestinal flora during the study. | 10 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| AYA Oren, MD | Contact | 972-9-7471017 | aya.oren@clalit.org.il |
| Name | Affiliation | Role |
|---|---|---|
| Timna Naftali, MD | Meir MC | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gastroenterology institute Meir Hospital | Recruiting | Kfar Saba | Israel |
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| ID | Term |
|---|---|
| D043183 | Irritable Bowel Syndrome |
| ID | Term |
|---|---|
| D003109 | Colonic Diseases, Functional |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D005767 | Gastrointestinal Diseases |
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| Placebo | Dietary Supplement | placebo |
|
| D004066 | Digestive System Diseases |