• standard techniques will be used
• maximal vasodilatation after nitro application
• baseline angiography with at least two orthogonal views (showing target lesion free of foreshortening or vessel overlap)
• 6 French guiding catheter at least
• target lesion will be crossed with standard guidewire
• direct stenting at the discretion of the investigator
• if pre-dilation, a commercially available balloon will be used (length not exceeding the stent to be implanted)
• full lesion coverage will be ensured (with one or more stents)
• only insert assigned stent type
• BMS needs to be fully embedded in vessel wall
• post-dilation with high pressure is required before treatment with DEB
• DEB will be inflated with nominal pressure (balloon equates to vessel diameter)
• length of DEB should exceed the BMS by 2-3 mm on each side
• if dissection, full length of dissection and optional additional stented area should be treated with additional DEB (to avoid geographic miss)

consisting of the composite of cardiac death, myocardial infarction (Q-wave and Non-Q wave) localized at the territory supplied by the treated vessel or target vessel revascularization (TVR) by either percutaneous coronary intervention or bypass graft surgery in the overall population

defined as the composite of cardiovascular death, stroke, myocardial infarction (MI) or ischemia-driven target lesion revascularization (TLR), as well as the individual components of target vessel revascularization (TVR) and Major adverse cardiac events (MACE) and stent thrombosis