The primary objective is to assess the safety and tolerability of the GLP-1 peptide analogue CM3.1-AC100 after repeated subcutaneous (sc) doses.

Inclusion Criteria:

• Provision of signed and dated informed consent prior to any study specific procedures;
• Male volunteer aged 18 to 50 years at Screening, both inclusive;
• Body weight between 60.0 to 100.0 kg (both inclusive) and BMI 19 to 29.9 kg/m2 (both inclusive)

Exclusion Criteria:

• Any history or presence of a clinically relevant disease as judged to be relevant by the Investigator: cardiovascular, pulmonary, gastro-intestinal, hepatic, renal, metabolic, haematological, neurologic, psychiatric, systemic, ocular or infectious disease and any acute infectious disease or signs of acute illness;
• Blood donation within 3 month before administration of the IP;
• Presence or history of drug allergy, or allergic disease diagnosed and treated by a physician