FIT (Fast Infarction Treatment): Complete Revascularization During Primary Percutaneous Coronary Intervention (PCI) Can be Achieved Safely With an Improved Clinical Outcome During the Indexed Hospitalization.

Phase III Study, Multivessel Percutaneous Treatment During Myocardial Infarction

Few reports described outcomes of complete compared with infarct related artery (IRA) only revascularization in patients with ST elevation myocardial infarction (STEMI) and multivessel coronary disease (CAD).

The purpose of this study is to determine outcome (death, myocardial infarction, target vessel failure) of 180 consecutive patients with STEMI and multivessel CAD undergoing primary angioplasty.

Before the first angioplasty patients are randomized to 2 different strategies: 1) culprit vessel angioplasty only, 2) staged revascularization.

Inclusion Criteria:

• myocardial acute infarction
• prolonged chest pain (>20 minute) started less <12 hours before arrive in hospital
• ST segment elevation of >1mm in >2 contiguous leads
• new left bundle branch block
• diameter of the coronary suitable of angioplasty >2mm
• the patients agrees to the study protocol and provides a written consensus
• two or more coronary suitable for angioplasty

Exclusion Criteria:

• refused written consensus
• hypersensitivity or contraindication to any of the following medications: heparin bivalirudin aspirin prasugrel stainless steel
• history of bleeding
• cardiogenic shock (PA < 90mmHg)
• chronic total occlusion in the second lesion
• TIMI Flow < II in the culprit lesion
• recent pregnancy
• history of intra-cerebral major hemorrhagic stroke
• an elective surgical procedure is planned that would necessitate interruption of thienopyridines during the first six months post enrollment life expectancy <1 year