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Seborrheic keratoses (SK's) are very common, but harmless skin lesions that commonly appear during adult life. Patients with seborrheic keratoses frequently desire treatment due to symptoms of itching and irritation or for cosmetic purposes. Seborrheic keratoses can be easily removed and have been treated in a number of different ways. Two of the simplest and most successful ways to remove seborrheic keratoses are cryosurgery and curettage.
The investigators are conducting this study to see which of these two treatments has the best result.
Approximately 24-30 people will take part in this research study at the Hershey Medical Center.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cryosurgery | Active Comparator | One lesion on the patients' trunk or proximal extremities will be treated with cryosurgery. |
|
| Curettage | Active Comparator | One lesion on one side of the patients' trunk or proximal extremities will be treated by curettage. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cryosurgery | Procedure | freezing of lesion with liquid nitrogen |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Partial or complete resolution of treated lesion. | Follow up evaluation by a blinded physician along with the gathering of patient information via questionnaires will be obtained at the completion of the study. | 6 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lance D. Wood, M.D. | Milton S. Hershey Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Penn State Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19465852 | Background | Brodsky J. Management of benign skin lesions commonly affecting the face: actinic keratosis, seborrheic keratosis, and rosacea. Curr Opin Otolaryngol Head Neck Surg. 2009 Aug;17(4):315-20. doi: 10.1097/MOO.0b013e32832d75e3. | |
| 15090020 | Background | Herron MD, Bowen AR, Krueger GG. Seborrheic keratoses: a study comparing the standard cryosurgery with topical calcipotriene, topical tazarotene, and topical imiquimod. Int J Dermatol. 2004 Apr;43(4):300-2. doi: 10.1111/j.1365-4632.2004.02282.x. |
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| ID | Term |
|---|---|
| D017492 | Keratosis, Seborrheic |
| ID | Term |
|---|---|
| D007642 | Keratosis |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| D003452 | Cryosurgery |
| D003475 | Curettage |
| ID | Term |
|---|---|
| D055011 | Ablation Techniques |
| D013514 | Surgical Procedures, Operative |
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| Curettage |
| Procedure |
the lesion will be anesthetized and destroyed with a curette. |
|