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| Name | Class |
|---|---|
| University of Nairobi | OTHER |
| Canadian International Development Agency | OTHER_GOV |
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Optimal development of sustainable health systems must use locally relevant infrastructure. Mobile phone technology, driven primarily by local market forces rather than foreign assistance, is spreading rapidly through African communities to improve people's personal and business communications. Here, the investigators propose using a structured mobile phone communications system for prevention of mother to child transmission of HIV (PMTCT). The system is designed to improve antenatal linkage to care, provide reminders to take PMTCT medications, and improve post-natal support and follow-up, even when mothers deliver at home. In addition to benefits in PMTCT related outcomes, this model allows evaluation of the intervention in a public health setting with the ultimate goal of advancing regional health systems development. The overall goal of of the study is to assess if mobile phones and SMS text messages can be used to help improve prevention of maternal to child transmission (PMTCT) of HIV services by strengthening health systems.
Specific objectives are:
1. To determine if mobile phone SMS text messages can demonstrate an improvement in compliance with a known intervention ( use of nevirapine) for PMTCT, demonstrated by:
1a) improved antenatal care attendance (greater than 4 visits)
1b) increased usage of nevirapine in labour (from 60% to at least 70%)
1c) earlier identification and treatment of HIV positive infants
1d) increased postpartum care for HIV positive mothers
1e) acceptability of cell phone SMS text messages transmission of information among HIV positive women
2. To demonstrate that mobile phone technology can be used as an effective tool to strengthen PMTCT health information systems at the facility level by: 2a) determining factors that constrain or promote the use of cell phone technology to strengthen PMTCT health information systems from the perspective of patients, health care providers and policy makers 2b) determining how cell phones can be used as a tool to generate equity statistics for PMTCT programs and formulate equity orientated PMTCT policies 2c) determine if early involvement of policy makers in the study improves knowledge translation
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| cell phone sms messages | Experimental | The experimental arm will receive the cell phone SMS text messaging intervention. |
|
| Control | No Intervention | The control group will receive the standard of care but no SMS text messages. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cell phone sms text messaging | Behavioral | At enrollment a study nurse will send the intervention group a weekly SMS message reminding them to attend antenatal care. Starting at 36 weeks gestational age, an automated bulk SMS management system, will send the intervention group 3 SMS text messages (using non descript slogans) each week by proxy reminding them to take their nevirapine in labor. From time of delivery to 6 weeks postpartum the women will aslo receive 3 SMS messages per week reminding them to attend their 6 week checkup and 6 week infant visit.Upon receiving these messages women in the intervention group can text back if they have any concerns or questions. These women would then receive phone calls from the study nurse triaged according to the women's needs. |
| Measure | Description | Time Frame |
|---|---|---|
| increased nevirapine uptake in labour in pregnant HIV positive women from 60% to 70% | At time of delivery and/or postpartum visit |
| Measure | Description | Time Frame |
|---|---|---|
| HIV positive rates in infants born to mothers in the study | assessed at birth, 6 weeks and 3 months of age | |
| number of antenatal care visits | assessed at time of 6 week postpartum visit | |
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Inclusion Criteria:
Women will be eligible to participate if they:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Joshua Kimani, MD | Contact | jkimani@csrtkenya.org | ||
| Lisa S Avery, MD | Contact | 1-204 272 3150 | avery@cc.umanitoba.ca |
| Name | Affiliation | Role |
|---|---|---|
| Joshua Kimani, MD | University of Manitoba and University of Nairobi | Principal Investigator |
| Peter Cherutich, MD | Ministry of Health, NASCOP Kenya | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pumwani Maternity Hospital | Recruiting | Nairobi | Kenya |
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| ID | Term |
|---|---|
| D015658 | HIV Infections |
| ID | Term |
|---|---|
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D015229 | Sexually Transmitted Diseases, Viral |
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| earlier identification and treatment of HIV positive infants |
| at 6 week infant visit |
| acceptability fo smsm messages for PMTCT related care | at 6 week postpartum visit |
| Mary Gichuihi, Masters |
| University of Nairobi |
| Study Director |
| D012749 | Sexually Transmitted Diseases |
| D016180 | Lentivirus Infections |
| D012192 | Retroviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |