Safety and Efficacy Study of AGN-214868 in Patients With Idiopathic Overactive Bladder and Urinary Incontinence

This study will evaluate the safety and efficacy of AGN-214868 in patients with idiopathic overactive bladder (IOAB) and urinary incontinence.

Inclusion Criteria:

• If female, must be of nonreproductive potential
• If male, must agree to use acceptable contraception
• Symptoms of overactive bladder with urinary urgency incontinence
• Inadequate response or limiting side effects with anticholinergics for the treatment of OAB

Exclusion Criteria:

• Overactive bladder caused by neurological condition (eg, spinal cord injury, multiple sclerosis)
• History of bladder surgery
• Treatment with botulinum toxin therapy of any serotype for any non-urological condition within the prior 12 weeks
• Previous treatment with botulinum toxin therapy of any serotype for any urological condition