Effect of Enzyme Therapy on Protein Metabolism in Chronic Pancreatitis

Pancreatic exocrine insufficiency is known to impair nutrient absorption, especially fat, but few data exist about protein absorption. We aimed to investigate this question and assess the enzyme substitution efficiency using a sensitive method.

Inclusion Criteria:

• Chronic pancreatitis
• Pancreatic insufficiency
• Enzyme therapy treatment

Exclusion Criteria:

• Hepatic failure
• Pregnancy
• Positive serology to HIV, HCV, AGHbS, gastro-intestinal disease