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| Name | Class |
|---|---|
| National Research Agency, France | OTHER |
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The project aims to precisely quantify the postprandial amino acid utilization of egg proteins in vivo in humans, and also to assess their satiating power, in relation with nutrient postprandial waves and incretin secretions. For that purpose, 2 independent studies are conducted. The first one is realized using stable isotopes on 8 volunteers ingesting an egg test meal. The second one is a cross over design performed on 30 volunteers to compare the satiating effect of 2 equivalent snacks: whole eggs or cottage cheese.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Egg | Experimental |
| |
| Cottage cheese | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Egg snack | Dietary Supplement | subject consume 4 cooked whole eggs, providing 380 kcal |
| |
| Measure | Description | Time Frame |
|---|---|---|
| energy intake at lunch following the snack | ||
| Dietary amino acid utilization | transfer of stables isotopes used as intrinsic markers of egg proteins to metabolic pools |
| Measure | Description | Time Frame |
|---|---|---|
| plasma incretin concentrations | insulin, glucagon, GLP-1, PYY, ghrelin, GIP | |
| postprandial nutrient waves | plasma glucose, cholesterol, triglyceride, urea |
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Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre de recherche sur volontaires | Bobigny | 93 | France | |||
| Centre de recherche sur Volontaires |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23274906 | Derived | Fromentin C, Tome D, Nau F, Flet L, Luengo C, Azzout-Marniche D, Sanders P, Fromentin G, Gaudichon C. Dietary proteins contribute little to glucose production, even under optimal gluconeogenic conditions in healthy humans. Diabetes. 2013 May;62(5):1435-42. doi: 10.2337/db12-1208. Epub 2012 Dec 28. |
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| ID | Term |
|---|---|
| D005247 | Feeding Behavior |
| ID | Term |
|---|---|
| D001522 | Behavior, Animal |
| D001519 | Behavior |
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| Cottage cheese |
| Dietary Supplement |
Subjects consume 200 g of cottage cheese, providing 380 kcal |
|
| neoglucogenesis | Endogenous production of glucose and contribution of dietary amino acids |
| Nantes |
| 44 |
| France |