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| Name | Class |
|---|---|
| Rush University | OTHER |
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Recent clinical trials in non diabetics showed that vitamin D supplementation markedly reduced serum levels of C-reactive protein (CRP), interleukin-6, and tissue matrix metallo-proteinases. Our study objective is to evaluate if administration of vitamin D in African Americans with hypovitaminosis D and DM Type 2 decreases serum levels of inflammatory/thrombotic markers such as CRP: Highly Sensitive C Reactive Protein.
Other questions in our study: In diabetic African American patients,
Setting: All visits will take place at the Fantus Diabetes Clinic.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ergocalciferol | Active Comparator | The investigators will give intervention group 12 weeks of Vitamin D (ergocalciferol 50,000 units every week) |
|
| Placebo pill | Placebo Comparator | The investigators will give intervention group 12 weeks of placebo pill (in pill every week) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ergocalciferol | Drug | Active Comparator: Ergocalciferol The investigators will give intervention group 12 weeks of Vitamin D (ergocalciferol 50,000 units every week) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Levels of inflammatory markers | baseline and 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Levels of Vitamin D, PTH and Calcium | Baseline and 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Leon Fogelfeld, MD | Cook County Health | Study Director |
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| ID | Term |
|---|---|
| D014808 | Vitamin D Deficiency |
| D003920 | Diabetes Mellitus |
| ID | Term |
|---|---|
| D001361 | Avitaminosis |
| D003677 | Deficiency Diseases |
| D044342 | Malnutrition |
| D009748 | Nutrition Disorders |
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| ID | Term |
|---|---|
| D004872 | Ergocalciferols |
| D014807 | Vitamin D |
| ID | Term |
|---|---|
| D002782 | Cholestenes |
| D002776 | Cholestanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
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|
| Placebo pill | Drug | The investigators will give control group 12 weeks of 1 placebo pill every week. |
|
| D009750 |
| Nutritional and Metabolic Diseases |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D004700 | Endocrine System Diseases |
| D011083 |
| Polycyclic Compounds |
| D013261 | Sterols |
| D012632 | Secosteroids |
| D008563 | Membrane Lipids |
| D008055 | Lipids |